Pre-operative weight loss

GLP-1 weight loss before surgery.

Many surgeons set a target BMI or require weight loss before elective procedures — including orthopedic, bariatric, and other surgeries — to reduce anesthesia and complication risk. Mazrek's licensed providers can prescribe compounded semaglutide or tirzepatide to support that goal, on a timeline coordinated with your surgical team. Care starts with a short online intake and, if appropriate, ships directly to your door.

Why BMI matters before surgery

Higher BMI is associated with increased risk of anesthesia complications, wound healing problems, infection, and longer recovery times. That's why many surgical practices set a specific BMI threshold, or ask patients to lose a percentage of body weight, before scheduling a procedure. Reaching that target ahead of time can keep your surgery on schedule and reduce avoidable delays.

Mazrek handles the GLP-1 portion of your care

The independent licensed providers Mazrek connects you with prescribe and manage your GLP-1 treatment — your surgeon or referring physician stays in charge of your surgical clearance, timeline, and pre-operative requirements. GLP-1 medications slow gastric emptying, which is relevant to anesthesia and aspiration risk, so share your surgery date with your Mazrek provider and follow your surgical team's instructions on whether to pause treatment before your procedure.

Pricing

Compounded semaglutide starts at $89/month and compounded tirzepatide starts at $139/month, both on a 12-month plan — flat at every dose, with no separate membership fee. Medication and provider care are included.

See full pricing

Medication is prepared by VialsRx, a licensed U.S. pharmacy. Prescribed by independent licensed providers through Arora Health.

Compounded semaglutide and tirzepatide are not FDA-approved. They are not a substitute for surgery, a surgical weight-loss requirement, or your surgeon's clearance process. Mazrek does not guarantee any specific amount of weight loss, that you will meet a particular BMI target, or that you will be cleared for surgery. Individual results vary. Always follow your surgical team's pre-operative instructions, including any guidance on pausing GLP-1 medication before your procedure.

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