Prescription weight loss medication

Compounded Tirzepatide

Tirzepatide is a dual GIP and GLP-1 receptor agonist. Compounded tirzepatide is a custom-prepared medication that an independent licensed provider may prescribe. It is not FDA-approved.

Not FDA-approved. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness, or quality. They are prepared by state-licensed pharmacies on a provider's prescription for an individual patient.

Formulation

Compounded semaglutide and compounded tirzepatide are offered as injectable medication prepared by VialsRx, a licensed U.S. pharmacy. Which medication and formulation you receive is decided by your provider, and is subject to clinical eligibility and current availability.

Compounded Tirzepatide vs. Compounded Semaglutide

How it differs from semaglutide

Semaglutide and tirzepatide are both compounded GLP-1 medications, but they aren't the same drug. Tirzepatide acts on two hormonal pathways, the GLP-1 and GIP receptors. Semaglutide acts on one, the GLP-1 receptor alone. That mechanical difference is what separates the two medications, not a difference in how they're prescribed, dosed, or shipped through Mazrek.

Who typically considers tirzepatide

Tirzepatide is often considered by people who have already tried a single-pathway GLP-1 medication and are looking at a dual-pathway option with their provider, or by people whose provider recommends starting with a dual-pathway approach based on their health history and goals. Whether tirzepatide, semaglutide, or neither is right for you is a clinical decision your provider makes after reviewing your health history, not something you choose off a menu.

This page is not a substitute for medical advice, and it doesn't claim one medication works better than the other. Individual response varies, and only your provider can decide which medication, if any, fits your health history and goals. See Compounded Semaglutide.

Pricing

Starting at $139/month on the 12-month plan. The price is the same at every dose, so there is no pricing by dose. See all GLP-1 pricing.

Compounded Tirzepatide pricing by plan length
Plan	Price per month	Billing frequency	Total charged at checkout
Monthly	$209/mo	Every month	$209
3 months	$179/mo	Every 3 months (quarterly)	$537 for 3 months
6 months	$159/mo	One payment, up front	$954 for 6 months
12 months	$139/mo	One payment, up front	$1,668 for 12 months

What's included

Review of your health intake by a licensed U.S. provider
If prescribed, the medication, prepared by VialsRx, a licensed U.S. pharmacy
Injection supplies
Free shipping, typically 2 to 5 days
Secure messaging with your care team and dose adjustments by your provider
No membership fee

How eligibility and prescribing work

You complete a short online health intake. A licensed U.S. provider reviews it. Not everyone is prescribed treatment.
Mazrek is a technology platform. Prescribing decisions are made only by the independent licensed provider, never by Mazrek.
Your provider decides whether treatment is appropriate, which medication, and your dose and titration schedule.
You must be 18 or older.
If you are not a candidate, no prescription is issued.

Safety information

Boxed warning: thyroid C-cell tumors

In rodent studies, tirzepatide caused thyroid C-cell tumors. It is not known whether it does in humans, including medullary thyroid carcinoma (MTC).
Do not use if you or a family member has had MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Tell your provider right away about a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath.

Common side effects

Nausea
Diarrhea
Vomiting
Constipation
Stomach pain
Indigestion and reflux

Serious risks to report immediately

Pancreatitis (severe, persistent abdominal pain, with or without vomiting)
Gallbladder problems, including gallstones
Dehydration and kidney problems, usually after vomiting or diarrhea
Serious allergic reactions (swelling of the face, lips or throat, trouble breathing)
Low blood sugar, especially if you also take insulin or sulfonylureas
Changes in vision, for people with diabetic retinopathy

Other things to know

Tirzepatide may make oral birth control less effective. Ask your provider about a backup method.
It slows stomach emptying, which can affect how other oral medications are absorbed.

Who should not use it

People who are pregnant, planning pregnancy, or breastfeeding
Anyone allergic to tirzepatide or any ingredient in the preparation
Anyone with a personal or family history of MTC or MEN 2

This is general information, not medical advice, and it is not a complete list of risks. Your provider will review risks with you before prescribing. In an emergency, call 911. You can report side effects to your care team at support@joinmazrek.com or to the FDA at www.fda.gov/medwatch. See also Safety & Legal.

Billing, shipping and renewal

Dose-based pricing: There is none. The price is the same at every dose. If your provider raises or lowers your dose, your price doesn't change.
Membership fees: No membership fee. The plan price covers your medication, provider care, and injection supplies.
Shipping: Shipping is included at no extra charge, typically 2 to 5 days, to all 50 states.
Renewal: Plans renew automatically at the end of each term at the rate shown for that term. You can cancel or pause through your patient portal, or by emailing support@joinmazrek.com, before your next billing date. Cancellation applies to future renewals only.
Refunds: Refund eligibility depends on how far your order has progressed. Once a prescription has been sent to the pharmacy, the order is final. Read the full refund policy in the Terms of Service.
Insurance: Mazrek is cash-pay and does not bill insurance.

Common questions

No. Compounded tirzepatide is custom-prepared by a licensed pharmacy for an individual patient. The FDA does not review it for safety, effectiveness, or quality.

No. The plan price is the same at every dose.

See if you qualify

The intake is only needed if you decide to start treatment.